LEXICON PHARMACEUTICALS, INC./DE (LXRX) is a publicly traded company in the Unknown sector. Across all available filings, 39 corporate insiders have executed 739 transactions totaling $581.8M, demonstrating a bullish sentiment with $581.0M in net insider flow. The most recent transaction on Feb 23, 2026 involved a purchase of 100,000 shares valued at $147.0K.
No significant insider buying has been recorded for LXRX in the recent period.
No significant insider selling has been recorded for LXRX in the recent period.
Based on recent SEC filings, insider sentiment for LXRX is bullish with an Insider Alignment Score of 100/100 and a net flow of $581.0M. Insiders are accumulating shares, which historically signals confidence in the company's future performance.
Insider trading at LEXICON PHARMACEUTICALS, INC./DE (LXRX) refers to stock transactions made by corporate insiders—executives, directors, and beneficial owners holding more than 10% of the company's shares. These individuals have access to material non-public information and are required by law to report their trades to the SEC within two business days. Currently, 39 insiders are actively trading LXRX stock, having executed 739 transactions in the past 90 days. The most active insider is Advisors, L.l.c. Invus (Executive), who has made 7 transactions totaling $231.8M.
Get notified when executives and directors at LXRX file new Form 4 transactions
Date | Insider | Title | Type | Shares | Price | Value | Flags |
|---|---|---|---|---|---|---|---|
| Feb 23, 2026 | Debbane Raymond | Executive | Purchase | 100,000 | $1.47 | $147.0K | |
| Feb 20, 2026 | Debbane Raymond | Executive | Purchase | 100,000 | $1.48 | $147.8K | |
| Feb 19, 2026 | Debbane Raymond | Executive | Purchase | 50,000 | $1.44 | $72.0K | |
| May 10, 2024 | S.a. Artal Group | Executive | Option Exercise | 57,546,100 | $N/A | $0 | |
| Apr 28, 2024 | Amouyal Philippe | Executive | Option Exercise | 8,032 | $N/A | $0 | |
| Apr 28, 2024 | L. Barker Sam | Executive | Option Exercise | 8,032 | $N/A | $0 | |
| Apr 28, 2024 | Debbane Raymond | Executive | Option Exercise | 8,032 | $N/A | $0 | |
| Apr 28, 2024 | J. Lefkowitz Robert Md | Executive | Option Exercise | 8,032 | $N/A | $0 | |
| Apr 28, 2024 | J. Sobecki Christopher | Executive | Option Exercise | 8,032 | $N/A | $0 | |
| Apr 28, 2024 | L. Swain Judith | Executive | Option Exercise | 8,032 | $N/A | $0 | |
| Mar 13, 2024 | Westend Stichting Administratiekantoor | Executive | Award | 1,150,922 | $108.50 | $124.9M | Large |
| Feb 28, 2024 | Coats Lonnel | Executive | Option Exercise | 33,333 | $N/A | $0 | |
| Feb 28, 2024 | Coats Lonnel | Executive | Option Exercise | 91,364 | $N/A | $0 | |
| Feb 28, 2024 | Coats Lonnel | Executive | Payment | 61,371 | $2.62 | $160.8K | |
| Feb 28, 2024 | Coats Lonnel | Executive | Option Exercise | 120,383 | $N/A | $0 |
| TYPE | COUNT | VALUE | % |
|---|---|---|---|
Purchase(P) | 232 | $581.4M | 81.5% |
Award(A) | 77 | $124.9M | 17.5% |
Payment(F) | 112 | $4.7M | 0.7% |
Exercise (Options)(X) | 2 | $1.8M | 0.3% |
Sale(S) | 6 | $391.5K | 0.1% |
Exercise(M) | 305 | $286.3K | 0.0% |
Gift(G) | 4 | $0 | 0.0% |
Other(J) | 1 | $0 | 0.0% |
Insiders at LEXICON PHARMACEUTICALS, INC./DE are accumulating shares at an accelerated pace. With 39 insiders making 739 transactions totaling $581.4M in purchases versus $391.5K in sales, the net buying activity of $581.0M signals strong executive confidence. Advisors, L.l.c. Invus (Executive) leads the buying activity with $231.8M in transactions across all time.