Prime Medicine, Inc. (PRME) is a publicly traded company in the Unknown sector. Across all available filings, 17 corporate insiders have executed 90 transactions totaling $162.6M, demonstrating a bullish sentiment with $122.6M in net insider flow. The most recent transaction on Feb 23, 2026 involved a transaction of 140,000 shares valued at $0.
No significant insider buying has been recorded for PRME in the recent period.
No significant insider selling has been recorded for PRME in the recent period.
Based on recent SEC filings, insider sentiment for PRME is bullish with an Insider Alignment Score of 88/100 and a net flow of $122.6M. Insiders are accumulating shares, which historically signals confidence in the company's future performance.
Insider trading at Prime Medicine, Inc. (PRME) refers to stock transactions made by corporate insiders—executives, directors, and beneficial owners holding more than 10% of the company's shares. These individuals have access to material non-public information and are required by law to report their trades to the SEC within two business days. Currently, 17 insiders are actively trading PRME stock, having executed 90 transactions in the past 90 days. The most active insider is Robert Nelsen (Executive), who has made 7 transactions totaling $43.6M.
Get notified when executives and directors at PRME file new Form 4 transactions
Date | Insider | Title | Type | Shares | Price | Value | Flags |
|---|---|---|---|---|---|---|---|
| Feb 23, 2026 | Alenson Carman | See Remarks | Award | 140,000 | $N/A | $0 | |
| Aug 1, 2025 | Gillis Steven | Executive | Purchase | 3,030,300 | $3.30 | $10.0M | Large |
| Aug 1, 2025 | Fund Xii, L.p. Arch Venture | Executive | Purchase | 3,030,300 | $3.30 | $10.0M | Large |
| Aug 1, 2025 | Nelsen Robert | Executive | Purchase | 3,030,300 | $3.30 | $10.0M | Large |
| Aug 1, 2025 | Alphabet Inc. | Executive | Purchase | 1,500,000 | $3.30 | $5.0M | Large |
| Jun 30, 2025 | R. Liu David | Executive | Purchase | 21,000 | $2.52 | $52.9K | |
| Jun 5, 2024 | Michael Gottesdiener Keith | Executive | Gift | 250,000 | $N/A | $0 | |
| Jun 5, 2024 | Michael Gottesdiener Keith | Executive | Gift | 250,000 | $N/A | $0 | |
| Feb 15, 2024 | Partners X, L.p. Arch Venture | Executive | Purchase | 3,200,000 | $6.25 | $20.0M | Large |
| Feb 15, 2024 | Partners Xii, Llc Arch Venture | Executive | Purchase | 3,200,000 | $6.25 | $20.0M | Large |
| Feb 15, 2024 | Nelsen Robert | Executive | Purchase | 3,200,000 | $6.25 | $20.0M | Large |
| Nov 11, 2023 | Michael Gottesdiener Keith | Executive | Gift | 5,000 | $N/A | $0 | |
| Nov 11, 2023 | Michael Gottesdiener Keith | Executive | Gift | 7,500 | $N/A | $0 | |
| Jul 21, 2023 | R. Liu David | Executive | Gift | 1,000,000 | $N/A | $0 | |
| Jul 21, 2023 | R. Liu David | Executive | Gift | 1,000,000 | $N/A | $0 |
| TYPE | COUNT | VALUE | % |
|---|---|---|---|
Purchase(P) | 14 | $142.6M | 87.7% |
Sale(S) | 33 | $20.0M | 12.3% |
Award(A) | 1 | $0 | 0.0% |
Gift(G) | 6 | $0 | 0.0% |
Other(J) | 22 | $0 | 0.0% |
Conversion(C) | 14 | $0 | 0.0% |
Insiders at Prime Medicine, Inc. are accumulating shares at an accelerated pace. With 17 insiders making 90 transactions totaling $142.6M in purchases versus $20.0M in sales, the net buying activity of $122.6M signals strong executive confidence. Robert Nelsen (Executive) leads the buying activity with $43.6M in transactions across all time.