Spyre Therapeutics, Inc.
Spyre Therapeutics, Inc. (SYRE) is a publicly traded company in the Unknown sector. Across all available filings, 8 corporate insiders have executed 17 transactions totaling $2.0M, demonstrating a bearish sentiment with -$2.0M in net insider flow. The most recent transaction on Jan 21, 2026 involved a transaction of 63,227 shares valued at $0.
SYRE Insider Activity Summary
Who Is Buying SYRE Stock?
No significant insider buying has been recorded for SYRE in the recent period.
Who Is Selling SYRE Stock?
No significant insider selling has been recorded for SYRE in the recent period.
Is Spyre Therapeutics, Inc. Insider Trading Bullish or Bearish?
Based on recent SEC filings, insider sentiment for SYRE is bearish with an Insider Alignment Score of 0/100 and a net flow of -$2.0M. Insiders are reducing their positions, though this can be driven by factors unrelated to company outlook.
SYRE Frequently Asked Questions
Understanding SYRE Insider Activity
Insider trading at Spyre Therapeutics, Inc. (SYRE) refers to stock transactions made by corporate insiders—executives, directors, and beneficial owners holding more than 10% of the company's shares. These individuals have access to material non-public information and are required by law to report their trades to the SEC within two business days. Currently, 8 insiders are actively trading SYRE stock, having executed 17 transactions in the past 90 days. The most active insider is Cameron Turtle (Executive), who has made 6 transactions totaling $1.5M.
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Track Spyre Therapeutics, Inc. Insider Activity
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