James Karrels serves as Executive at MACROGENICS INC, where they oversee executive responsibilities. Since joining the company, James Karrels has executed 30 insider transactions totaling $1.4M, demonstrating a bearish approach to their equity position. Their most recent transaction on Feb 8, 2026 involved exercising options for 9,999 shares valued at $0.
James Karrels currently holds 9,999 shares of MACROGENICS INC (MGNX), valued at approximately $0. This represents their equity stake as Executive.
Based on SEC Form 4 filings, James Karrels has been a net seller of MGNX stock. They have purchased $98.8K and sold $1.3M worth of shares.
James Karrels's most recent insider trade was on Feb 8, 2026, when they sold 9,999 shares at $0.00 per share.
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| $1.81 |
| Discretionary |
| Feb 8, 2026 | MGNX | $0 | Option Exercise | 9,999 | $N/A | Discretionary |
| Feb 7, 2026 | MGNX | $0 | Option Exercise | 6,334 | $N/A | Discretionary |
| Feb 7, 2026 | MGNX | $4.4K | Payment | 2,446 | $1.81 | Discretionary |
| Feb 7, 2026 | MGNX | $0 | Option Exercise | 6,334 | $N/A | Discretionary |
| Mar 4, 2024 | MGNX | $615.0K | Sale | 30,000 | $20.50 | Planned |
| Feb 15, 2024 | MGNX | $0 | Option Exercise | 15,003 | $N/A | Discretionary |
| Feb 15, 2024 | MGNX | $92.7K | Payment | 5,327 | $17.40 | Discretionary |
| Jun 15, 2022 | MGNX | $98.8K | Purchase | 40,000 | $2.47 | Discretionary |
| Mar 28, 2022 | MGNX | $12.6K | Option Exercise | 8,316 | $1.51 | Discretionary |
| Mar 22, 2021 | MGNX | $495.0K | Sale | 15,000 | $33.00 | Discretionary |
| Jan 28, 2021 | MGNX | $7.5K | Option Exercise | 5,000 | $1.51 | Discretionary |
| Jan 28, 2021 | MGNX | $940 | Option Exercise | 1,000 | $0.94 | Discretionary |
| Mar 6, 2020 | MGNX | $4.2K | Option Exercise | 4,473 | $0.94 | Discretionary |
| Jan 30, 2020 | MGNX | $6.9K | Option Exercise | 7,320 | $0.94 | Discretionary |
| Jan 30, 2020 | MGNX | $4.9K | Option Exercise | 5,180 | $0.94 | Discretionary |
| Jan 24, 2019 | MGNX | $5.0K | Option Exercise | 5,326 | $0.94 | Discretionary |
| Jan 24, 2019 | MGNX | $1.9K | Option Exercise | 2,000 | $0.94 | Discretionary |
| Jan 8, 2019 | MGNX | $5.0K | Option Exercise | 5,314 | $0.94 | Discretionary |
| Dec 18, 2018 | MGNX | $4.7K | Option Exercise | 5,000 | $0.94 | Discretionary |
| Nov 27, 2018 | MGNX | $2.8K | Option Exercise | 3,000 | $0.94 | Discretionary |
| Mar 5, 2018 | MGNX | $155.0K | Sale | 5,000 | $31.00 | Discretionary |
| Jan 16, 2018 | MGNX | $6.1K | Option Exercise | 6,516 | $0.94 | Discretionary |
| Dec 29, 2017 | MGNX | $2.8K | Option Exercise | 3,000 | $0.94 | Discretionary |
| Sep 5, 2017 | MGNX | $4.7K | Option Exercise | 5,000 | $0.94 | Discretionary |
| Jan 25, 2017 | MGNX | $4.7K | Option Exercise | 5,000 | $0.94 | Discretionary |
| Jan 29, 2016 | MGNX | $9.4K | Option Exercise | 10,000 | $0.94 | Discretionary |
| Oct 7, 2015 | MGNX | $5.6K | Option Exercise | 6,000 | $0.94 | Discretionary |
| Dec 24, 2014 | MGNX | $3.9K | Option Exercise | 4,100 | $0.94 | Discretionary |