Stephen J. Hoffman serves as Executive at Sirtris Pharmaceuticals, Inc., where they oversee executive responsibilities. Since joining the company, Stephen J. Hoffman has executed 62 insider transactions totaling $21.5M, demonstrating a bullish approach to their equity position. Their most recent transaction on Oct 23, 2025 involved receiving (via award) 4,267 shares valued at $0.
Stephen J. Hoffman currently holds 8,859 shares of Sirtris Pharmaceuticals, Inc. (SIRT), valued at approximately $0. This represents their equity stake as Executive.
Based on SEC Form 4 filings, Stephen J. Hoffman has been a net buyer of SIRT stock. They have purchased $19.0M and sold $2.5M worth of shares.
Stephen J. Hoffman's most recent insider trade was on Oct 23, 2025, when they sold 4,267 shares at $0.00 per share.
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| $N/A |
| Discretionary |
| Oct 10, 2023 | ACRX | $0 | Award | 581 | $N/A | Discretionary |
| Jul 15, 2022 | ACRX | $0 | Award | 15,500 | $N/A | Discretionary |
| Dec 28, 2021 | DRNA | $618.0K | Tender | 16,157 | $38.25 | Discretionary |
| Jun 17, 2021 | ACRX | $0 | Award | 10,000 | $N/A | Discretionary |
| Jun 3, 2021 | DRNA | $0 | Option Exercise | 3,333 | $N/A | Discretionary |
| Dec 10, 2020 | DRNA | $0 | Other | 10,137 | $N/A | Discretionary |
| Aug 26, 2020 | DRNA | $0 | Other | 15,601 | $N/A | Discretionary |
| Jun 16, 2020 | ACRX | $0 | Award | 7,500 | $N/A | Discretionary |
| Jun 25, 2019 | ACRX | $0 | Award | 3,750 | $N/A | Discretionary |
| Nov 12, 2018 | ARPO | $60.3K | Purchase | 30,000 | $2.01 | Discretionary |
| Nov 9, 2018 | ARPO | $3.8K | Purchase | 1,967 | $1.95 | Discretionary |
| Mar 17, 2015 | GNCA | $5.8M | Purchase | 700,000 | $8.25 | Discretionary |
| Mar 7, 2014 | ACRX | $0 | Other | 1,300,000 | $N/A | Discretionary |
| Feb 10, 2014 | GNCA | $3.0M | Purchase | 250,931 | $12.00 | Discretionary |
| Feb 10, 2014 | GNCA | $0 | Conversion | 263,900 | $N/A | Discretionary |
| Feb 10, 2014 | GNCA | $0 | Conversion | 777,584 | $N/A | Discretionary |
| Feb 4, 2014 | DRNA | $3.0M | Purchase | 200,000 | $15.00 | Discretionary |
| Feb 4, 2014 | DRNA | $0 | Conversion | 312,000 | $N/A | Discretionary |
| Feb 4, 2014 | DRNA | $0 | Conversion | 179,322 | $N/A | Discretionary |
| Feb 4, 2014 | DRNA | $0 | Conversion | 1,043,429 | $N/A | Discretionary |
| Sep 4, 2012 | ALTH | $860.6K | Tender | 472,871 | $1.82 | Discretionary |
| Sep 4, 2012 | ALTH | $167.4K | Tender | 92,000 | $1.82 | Discretionary |
| Sep 4, 2012 | ALTH | $364 | Tender | 200 | $1.82 | Discretionary |
| Sep 4, 2012 | ALTH | $364 | Tender | 200 | $1.82 | Discretionary |
| Sep 4, 2012 | ALTH | $364 | Tender | 200 | $1.82 | Discretionary |
| Sep 4, 2012 | ALTH | $364 | Tender | 200 | $1.82 | Discretionary |
| May 29, 2012 | ACRX | $968.0K | Purchase | 284,698 | $3.40 | Discretionary |
| Dec 13, 2011 | ALTH | $0 | Award | 90,000 | $N/A | Discretionary |